Seerup Corbett (vinylsteven24)

9%) or palliative (1.2%) concept. Minor changes were found in 62/257 patients (24.1%). Invasive procedures and additional imaging were intended in 70/257 (27.2%) and 94/257 (36.6%) patients before PET/CT and 20/257 (7.8%) and 8/257 (3.1%) patients after PET/CT. Curative therapy concepts based on PET/CT were associated with a longer OS (3.5 yr.[95%CI 3.1-3.8 yr.]) as compared to palliative concepts (0.9 yr.[95%CI 0.6-1.2 yr.];p < 0.0001). Patients with SCC had a worse prognosis (2.4 yr.[95%CI 2.0-2.9 yr.]) as compared to patients with AC (3.2 yr.[95%CI 2.7-3.7 yr.];p = 0.01). In patients with advanced esophageal cancer, PET/CT has a significant impact on clinical management by improving the selection of individualized treatment strategies and avoiding additional diagnostic procedures. In patients with advanced esophageal cancer, PET/CT has a significant impact on clinical management by improving the selection of individualized treatment strategies and avoiding additional diagnostic procedures. To compare the image quality of the reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) with the full field-of-view (fFOV) DWI in the assessment of bladder cancer (BC); and to explore the possible superiority of bi-planar (axial and sagittal) rFOV DWI over single planar fFOV DWI in predicting muscle-invasiveness of BC. This retrospective study analyzed 61 patients with BC who underwent DWI sequences including axial fFOV DWI, axial rFOV DWI, and sagittal rFOV DWI. Qualitative and quantitative image quality assessment were compared between axial fFOV DWI and rFOV DWI sequences. The tumor with its base could be clearly displayed on DWI was defined as the evaluable lesion, and the number of evaluable lesions detected from single axial fFOV DWI, axial rFOV DWI, sagittal rFOV DWI, and bi-planar rFOV DWI sequences was recorded and compared. The apparent diffusion coefficient (ADC) was compared between non-muscular-invasive bladder cancer (NMIBC) and muscular-invasive bladder cancer (MIBC) based on the rve, 0.946) for predicting the presence of muscle-invasiveness of BC. Bi-planar rFOV DWI may provide more diagnostic confidence than the single planar DWI for predicting the presence of muscle-invasiveness in BC, with improved image quality over the fFOV DWI. Bi-planar rFOV DWI may provide more diagnostic confidence than the single planar DWI for predicting the presence of muscle-invasiveness in BC, with improved image quality over the fFOV DWI. To prospectively compare the diagnostic efficacy of conventional diffusion-weighted imaging (DWI) and diffusion kurtosis imaging (DKI) in differentiating between muscle-invasive bladder cancer (MIBC) and non-muscle-invasive bladder cancer (NMIBC). Multiple b value DWIs were performed using a 3-T magnetic resonance (MR) imaging unit in fifty-one patients with bladder cancer including MIBC and NMIBC confirmed by histopathological findings. DWI data were postprocessed using mono-exponential and DKI models to calculate the apparent diffusion coefficient (ADC), apparent diffusional kurtosis (K ), and kurtosis-corrected diffusion coefficient (D ). Receiver-operating characteristic (ROC) analysis was performed to compare the diagnostic efficacy of all diffusion parameters. All parameters differed significantly between MIBC and NIMBC including increased K , decreased D and ADC (all p < 0.001). Only the combination of D and K was significantly higher than ADC (p < 0.05), whilst D and K were not statistically different from ADC. Both conventional DWI and DKI models are beneficial in differentiating between MIBC and NMIBC, whilst the combination of D and K can produce a more robust value than conventional ADC value in evaluating aggressiveness of bladder cancer. Both conventional DWI and DKI models are beneficial in differentiating between M