Montgomery Jarvis (vaultletter0)

Epidemiological evidence for the association between traffic-related noise and the incidence of major cardiovascular events such as acute myocardial infarction (AMI) and congestive heart failure (CHF) is inconclusive, especially in North America. We evaluated the associations between long-term exposure to road traffic noise and the incidence of AMI and CHF. Our study population comprised ∼ 1 million people 30-100 years of age who lived in Toronto, Canada, from 2001 to 2015 and were free of AMI (referred to as the AMI cohort) or CHF (the CHF cohort) at baseline. Outcomes were ascertained from health administrative databases using validated algorithms. selleck kinase inhibitor Annual average noise levels were estimated as the A-weighted equivalent sound pressure level over the 24-h period (LAeq24) and during nighttime (LAeqNight), respectively, using propagation modeling, and assigned to participants' annual six-digit postal code addresses during follow-up. We calculated hazarrm exposure to UFPs and nitrogen dioxide. We found near-linear relationships between noise and the incidence of AMI and CHF with no evidence of threshold values. In this large cohort study in Toronto, Canada, chronic exposure to road traffic noise was associated with elevated risks for AMI and CHF incidence. https//doi.org/10.1289/EHP5809. In this large cohort study in Toronto, Canada, chronic exposure to road traffic noise was associated with elevated risks for AMI and CHF incidence. https//doi.org/10.1289/EHP5809.We designed a questionnaire to assess the prevalence of scientific misconduct and possible associated factors in tertiary hospitals in China. A total of 278 questionnaires were distributed to researchers in three tertiary hospitals, and 217 were returned. The top three influencing factors on scientific misconduct were individual morality (74.20%), pressure for promotion (65.90%), and pressure for publishing articles (63.59%). More than 50% of researchers thought the pressure for promotion, publication, and external funding were high or very high. Approximately 40% of researchers admitted having committed at least one of the nine listed forms of scientific misconduct, and 17.51% admitted having committed at least one of fabrication, falsification, or plagiarism. The most common scientific misconducts was inappropriate authorship (29.49%). Being a principal investigator or physician and higher pressure for promotion were associated with higher self-reported research misconduct severity score (RMSS) grade. Being female and better recognition of scientific integrity were related to lower RMSS grade. We recommend that the Chinese policy makers and hospitals pay more attention to increasing perceptions of scientific integrity, establish a more scientific evaluation system for promotion, and improve the auditing and surveillance of research. Much has been written from the social science perspective surrounding surgeons' stress and burn out. The literature is sparse in reference to scientific investigations of the hemodynamic effect of that stress. This prospective clinical study quantifies the physiologic impact of performing surgery upon the acute care surgeon. Over 2.5 years, monitoring devices were affixed to surgeons prior to entering the operating room, and physiologic variables were documented every 30 minutes. Qualifying cases were projected as being greater than 2 hours with a baseline preoperative measurement obtained. Variables recorded included blood pressure (BP), heart rate (HR), rate pressure product (RPP), oxygen saturation (O sat), and end-tidal carbon dioxide (ET CO ). Statistically significant differences ( < .05) were found between baseline data to the maximum recording during the surgical operation for BP (min 101 ± 6.6 (mmHg)-max 117 ± 5.1 (mmHg)), HR