Friedrichsen Kirkpatrick (tyvekangora7)
Electrochemical water splitting is an ideal pollution-free path to generate hydrogen at large scale, though the developing of highly catalytic electrocatalysts for water oxidation reaction at large current densities are still a fundamental challenge. In this work, we demonstrated a novel, high wettability water-oxidation electrocatalyst composed of amorphous NiFe layer and CoS film on commercial nickel foam via a two-step electrodeposition synthetic path. Benefiting from the strong interactions between NiFe layer and CoS film, enlarged surface active sites and enhanced wettability, CoS@NiFe/NF electrode exhibited outstanding water oxidation performance at 10 mA/cm 2 with an overpotential of 175 mV in 1 M KOH solution and steadily delivered a current density of 1 A/cm 2 at merely 330 mV in 30 wt% KOH solution. Even at large densities, the CoS@NiFe/NF hybrids also showed excellent water oxidation stability and corrosion resistance for at least 24 h. Such synergistic assembling approach to fabricate CoS@NiFe/NF heterostructure together with excellent OER performance may possess a promising strategy for rationally building and designing hetero-structural electrocatalysts towards highly efficient water oxidation reaction. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.The highest efficacy of oral propranolol is for infantile hemangioma (IH) in the proliferative phase. Evaluation of the effectiveness of oral propranolol is less established when it is administered in late infancy following the proliferative phase. We aimed to assess the clinical outcomes of pediatric patients managed by oral propranolol beyond the proliferative phase of IH. A retrospective cohort study in a tertiary healthcare referral center was conducted to track all patients with IH receiving systemic propranolol following the proliferative phase. Twenty-eight eligible patients were managed by 2-3mg/kg per day of oral propranolol for IH beyond the proliferative phase, defined at 9 months of age. The mean age at the initiation of propranolol was estimated at 11.25 (SD, 2.24) months. All eligible patients experienced some degree of clinical resolution, with the average improvement rate being estimated at 77.1 (SD, 16.1)%. Comparable results were achieved among patients who were placed on propranolol at an age older than 12 months and those managed between the age of 9 and 12 months. Nirmatrelvir in vivo No serious adverse events were observed during the follow-up duration. In conclusion, oral propranolol is a safe and effective treatment for patients with IH initiating this agent beyond the proliferative phase. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.By involving the public, citizen science runs against the grain of an idealized science that leaves out the human element, and thus provides new opportunities for ecological research and society. We classify the goals of citizen science in ecology and environment into four broad categories (1) scientific, (2) participant benefits, (3) community, and (4) policy. Although none of these goals have been well studied, we review the literature showing that these projects are most effective in tracking ecological trends over large swaths of space and time, and discuss the challenges of recruiting, training, retaining, and educating participants, maintaining and disseminating high-quality data, and connecting with the larger community and policy. Biomedical studies, where patients participate in their own treatment in randomized trials, provide an interesting comparison with citizen science in ecology, sharing challenges in recruitment and involvement of nonscientists and ethical conduct of research. Future study will help address the ethical difficulties and enhance ways for citizen science in ecology and the environment to complement scientific discovery, involve and educate the public, and guide policy founded in science and the local