Bullock Fanning (stampflower16)

y diet. The results of this review indicates that eHealth MHBC interventions achieve preliminary success in promoting physical activity and healthy diet behaviors among people with NCD. Future studies could improve the intervention design to achieve better intervention effectiveness. PROSPERO International Prospective Register of Systematic Reviews CRD42019118629; https//. PROSPERO International Prospective Register of Systematic Reviews CRD42019118629; https//. Translation of diabetes self-management education and support (DSMES) into a digital format can improve access, but few digital programs have demonstrated outcomes using rigorous evaluation metrics. The aim of this study was to evaluate the impact of a digital DSMES program on hemoglobin A (HbA ) for people with type 2 diabetes. A single-arm, nonrandomized trial was performed to evaluate a digital DSMES program that includes remote monitoring and lifestyle change, in addition to comprehensive diabetes education staffed by a diabetes specialist. A sample of 195 participants were recruited using an online research platform (Achievement Studies, Evidation Health Inc). The primary outcome was change in laboratory-tested HbA from baseline to 4 months, and secondary outcomes included change in lipids, diabetes distress, and medication adherence. At baseline, participants had a mean HbA of 8.9% (SD 1.9) and mean BMI of 37.5 kg/m (SD 8.3). The average age was 45.1 years (SD 8.9), 70% were women, and 67% were White. At 4-month follow up, the HbA decreased by 0.8% (P<.001, 95% CI -1.1 to -0.5) for the total population and decreased by 1.4% (P<.001, 95% CI -1.8 to -0.9) for those with an HbA of >9.0% at baseline. Diabetes distress and medication adherence were also significantly improved between baseline and follow up. This study provides early evidence that a digitally enhanced DSMES program improves HbA and disease self-management outcomes. This study provides early evidence that a digitally enhanced DSMES program improves HbA1c and disease self-management outcomes. Evidence suggests that health care data sharing may strengthen care coordination, improve quality and safety, and reduce costs. However, to achieve efficient and meaningful adoption of health care data-sharing initiatives, it is necessary to engage all stakeholders, from health care professionals to patients. Although previous work has assessed health care professionals' perceptions of data sharing, perspectives of the general public and particularly of seldom heard groups have yet to be fully assessed. This study aims to explore the views of the public, particularly their hopes and concerns, around health care data sharing. An original, immersive public engagement interactive experience was developed-The Can of Worms installation-in which participants were prompted to reflect about data sharing through listening to individual stories around health care data sharing. A multidisciplinary team with expertise in research, public involvement, and human-centered design developed this concept. The installatio health disparities, both at international and local levels, and on delivering patient-centered care. Incorporating the knowledge generated and focusing on co-designing solutions to tackle these concerns is critical to engage the public as active contributors and to fully leverage the potential of health care data use.In previous work, we showed that intrinsically disordered regions (IDRs) of proteins contain sequence-distributed molecular features that are conserved over evolution, despite little sequence similarity that can be detected in alignments (Zarin et al., 2019). Here, we aim to use these molecular features to pr