Allison Huffman (robertplay90)

To determine the distribution of the corneal asphericity coefficient (Q value) and related factors in an Iranian geriatric population. This population-based studywas conducted in 2019 in Tehran, usingstratified multistage random cluster sampling. The study population was ≥60years of age. Participants underwent corneal imagingusing a Pentacam HR. Mean keratometry, corneal astigmatism, central corneal thickness, anterior chamber depth and the overall anterior and posterior Q values (for 8mm chord diameter)were recorded. Axial length measurements were performed using the IOL Master 500. 2457 eyes of 2457 individuals were analysed. The mean age was 67.3±5.82years and 1479 (60.2%) were female.The mean Q value for the anterior corneal surface was -0.35±0.17 (95% CI -0.35 to -0.34). The anterior Q value showed a statistically significant inverse relationship with axial length and mean keratometry, and a significant direct association with anterior chamber depth and corneal astigmatism. The mean posterior Q value was -0.41±0.15 (95% CI -0.42 to -0.40). #link# The posterior Q value had a significant direct relationship with age, anterior chamber depth, mean keratometry and corneal astigmatism. The corneal Q values in this geriatric Iranian population were more negative than the values reported in most previous studies. Corneal asphericity was greater affected by ocular biometry and corneal curvature than demographic factors and refractive status. The corneal Q values in this geriatric Iranian population were more negative than the values reported in most previous studies. learn more was greater affected by ocular biometry and corneal curvature than demographic factors and refractive status. It is well known that the number of nevi varies with age. However, there are a few data in the literature concerning total nevus count at different ages. The aim of this study was to assess and compare the total nevus count among different age groups. The total nevus count was assessed in consecutive patients belonging to nine age groups. Median nevus count was calculated and compared for each age group. Multivariate logistic regression analysis was used to define the influence of sex and phototype on the association between nevus count and age. We enrolled 900 patients (461, 51.2% females), with a median age of 46years and a total of 18,136 nevi. Significant differences were found in the median total nevus count among all age groups (P<0.001), with a significant increase in the first two decades and a significant decrease after the age of 50years. A similar trend was also observed in subgroups. The differences observed in the total body nevus count among age groups were independent of sex and phototype. We demonstrate that the total nevus count significantly increases during childhood and gradually decreases in the elderly. We demonstrate that the total nevus count significantly increases during childhood and gradually decreases in the elderly.We thank Jansson & Sparrelid for their Letter to the Editor(1)regarding our publication(2). We stated that "based on our results, patients with liver metastases should not be offered therapeutic strategies suitable for early stages, in view of poor survival". Jansson(1) argues that "the role of surgery in multiple intrahepatic cholangiocarcinoma (iCCA) should not be dismissed without further analysis"; similar to Zhang's views(3). Conventional catheter ablation involves prolonged exposure to ionizing radiation, potentially leading to detrimental health effects. Minimal fluoroscopy (MF) represents a safer alternative, which should be explored. Data on the safety and efficacy of this technique are limited. Our hypothesis is that MF is of equal efficacy and safety to conventional catheter ablation with the use of fluoroscopy by performing a meta-analysis of both randomized controlled trials (RCTs)