Skovsgaard Middleton (roadbead6)

sociated with a 25.1% increase (95% CI, 10.2%-40.1%; p = 0.001) in DF/CFICU-30. Increasing Abbreviated Injury Scale for the head was associated with decreased DF/CF-ICU-30 by analysis of variance (p < 0.001). Nontrauma patients had higher incidence of postoperative abdominal sepsis and need for dialysis, while T was independently associated with increased delirium, perhaps because of traumatic brain injury. Therapeutic study, level IV. Therapeutic study, level IV. Appropriate interfacility transfers are a key component of highly functioning trauma systems but transfer of unsalvageable patients can overburden the resources of higher-level centers. We sought to identify the occurrence and associated reasons for futile transfers within our trauma system. Using prospectively collected data from our system database, a retrospective cohort study was conducted to identify patients who underwent interfacility transfer to our American College of Surgeons level I center. Adult patients from June 2017 to June 2019 who died, had comfort measures implemented, were discharged, or went to hospice care within 48 hours of admission without significant operation, procedure, or radiologic intervention were examined. Futility was defined as resulting in death or hospice discharge within 48 hours of transfer without major operative, endoscopic, or radiologic intervention. A total of 1,241 patients transferred to our facility during the study period. Four hundred seven patients had a port for referral will significantly improve appropriate allocation of health care resources. Economic; Care management, level IV. Economic; Care management, level IV. Despite the widespread institution of modern massive transfusion protocols with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving ultramassive transfusion (UMT) (defined as ≥20 U of packed red blood cells [RBCs]) in 24 hours) remains low and resource consumption remains high. Therefore, we aimed to identify factors associated with mortality in trauma patients receiving UMT in the modern resuscitation era. An Eastern Association for the Surgery of Trauma multicenter retrospective study of 461 trauma patients from 17 trauma centers who received ≥20 U of RBCs in 24 hours was performed (2014-2019). Multivariable logistic regression and Classification and Regression Tree analysis were used to identify clinical characteristics associated with mortality. The 461 patients were young (median age, 35 years), male (82%), severely injured (median Injury Severity Score, 33), in shock (median shock index, 1.2; base excess, -9), and transfused a median of 29 U of RBCs, 22 U of frhoracotomy can aid in prognostication. Prognostic, level III. Prognostic, level III. Normothermic machine perfusion (NMP) has become a clinically established tool to preserve livers in a near-physiological environment. However, little is known about the predictive value of perfusate parameters towards the outcomes after transplantation. Fifty-five consecutive NMP-livers between 2018-2019 were included. All of the livers were perfused on the OrganOx metra® device according to an institutional protocol. Transplant and perfusion data were collected prospectively. Forty-five livers were transplanted after NMP. Five livers stem from donors after circulatory death and 31 (68.9%) from extended criteria donors (ECD). Mean (SD) cold ischemia time (CIT) was 6.4 (2.3) hours; mean (SD) total preservation time 21.4 (7.1) hours. Early allograft dysfunction (EAD) occurred in 13/45 (28.9%) patients. Perfusate aspartate-aminotransferase (p=0.008), alanine-aminotransferase (p=0.006), lactate-dehydrogenase (p=0.007) and their development over time, alkaline phosphatase (p=0.013) and sodium (p=0.016) correlated with EAD. Number of perfusate platelets correlated with CIT-