Rossen Cochrane (radiobass4)

A clinico-epidemiological study was conducted at two veterinary hospitals in Dhaka to evaluate the prevalence of parvoviral enteritis (PVE) in dogs and feline panleukopenia (FPL) in cats, to detect factors associated with them, and to identify their common clinical signs. Clinico-epidemiological data were collected for a total of 88 dogs and 129 cats which were presented to the hospitals, entered into MS excel 2010, and then transferred to STATA-14 software for conducting descriptive and univariable statistical analyses (Fisher's exact test). The maps showing the spatial distribution of PVE and FPL were produced by using QGIS software version 2.18.13. PVE in dogs and FPL in cats had the highest prevalence compared to other diseases (34.1%; 95% confidence interval 24.3-44.9; = 88 and 20.2%; 95% confidence interval 13.6-28.1; = 129, respectively). Young age (43.8%), poor body condition (58.4%), and exotic breeds (44.2%) were significantly associated with the occurrence of PVE ( ≤ 0.05). Poor body tion. Solubility and bioavailability are crucial for maximizing the activity of an antiparasitic drug. This study aimed to develop a combined preparation for antiparasitic medicines using ivermectin (Iver), fenbendazole (FBZ), and triclabendazole (TBZ), considering their solubility, bioavailability, and activity. Innovative preparations in solid dispersions (SD) were obtained using the joint mechanical processing of drug substances with polyvinylpyrrolidone (PVP) in an LE-101 roller mill. The preparations' efficacy was studied in 140 sheep spontaneously infected with gastrointestinal Strongylata, , , and . The preparations were given individually to the sheep in the form of an aqueous suspension orally. Their effectiveness was evaluated using intravital and postmortem parasitological examinations. The results confirmed the increase in solubility of substances by 13-29 times. The experiments have shown the high efficacy of SD composition of FBZ/Iver/PVP (1/1/9) containing FBZ (at 3.0 mg/kg ) and Iver (s of these substances with PVP when SD is dissolved in water and the synergistic effect of the active substances of the preparations. The resulting complexes have increased solubility in water and bioavailability. The use of such an SD suggests a significant reduction in the dosages of FBZ and TBZ without losing parasiticidal activity. This study investigated the prevalence of in retail poultry shops, characterized the antibiotic resistance profile, and detected the genotypic pattern of virulence genes. Broiler meat ( = 90), intestinal content ( = 40), and environmental samples ( = 95) were collected for this study. Besides, hand swabs ( = 20) were obtained from the poultry shop workers and stool samples ( = 40) were collected from the outpatient clinics of Beni-Suef University Hospital, Egypt. MS-L6 The samples were subjected to isolation and identification of by conventional bacteriological examinations and biochemical tests, followed by confirmatory identification by the polymerase chain reaction. Among the collected samples ( 285), could be detected in 14.4% ( = 41/285) of the samples, where 30.0% ( = 12/40) of the intestinal content was positive. Similarly, 10.0% ( = 9/90), 15.0% ( = 3/20), and 12.5% ( = 5/40) of the samples of meat, hand swabs, and stools were found positive for , respectively. A total of 12 (12.6%) out of 95 environmental samples were positive for . Based on the antimicrobial sensitivity profile, most of the recovered isolates were multidrug-resistant against most commonly used antibiotics. The findings conclude that poultry shops play a vital role in transmitting to the consumers. Asymptomatic poultry shop workers should draw attention to their potentials for sprea