Agerskov Goldberg (quartgate9)
Ising type models of charging of conductive nanopores with ions have already been proposed and investigated for single file cylindrical or single layer slit nanopores. In such pores, the state of ions, the coulombic interactions of which are exponentially screened by their images in pore walls, was named superionic. In the present work we extend the analysis of the superionic state to nanopores that can accommodate multiple rows of ions. By grouping multiple charges in the same row into 'supercharges', we map the arrangement of ions in polarised electrodes on a multi-row Ising model in an external field. We investigate one-, two- and three-row cases, which we solve exactly, using a purpose-built semi-numerical transfer matrix method. For pores of different radii, which can accommodate the corresponding number of ion rows, we calculate the dependence of the electrical capacitance and stored energy density on electrode potential. As in charging the single file pores, we find that in narrower pores higher energy densities can be achieved at low applied potentials, while wider pores perform better as the voltage is increased.Colloidal gel networks appear in different scientific and industrial applications because of their unique properties. Molecular dynamics simulations could reveal the relation between molecular level and macroscopic properties of these systems. Nevertheless, the predictions of numerical simulations might depend on the specific form and parameters of interaction potentials. In this paper, a new effective interaction potential is used for characterizing the mechanical behavior of low volume fraction colloidal gels under large shear deformation. The findings are compared with those obtained from other available forms of interaction potentials in order to determine gel characteristics that are interaction potential independent. Furthermore, the macroscopic stress-strain behavior is discussed in terms of the behavior of different terms of the proposed interaction potential. The correlation between the stretch of interparticle bonds and their alignment in the direction of the maximum principal stress is also computed in order to provide microscopic explanations for the initial strain softening behavior. It is concluded that, in addition to topology, local mechanical interactions between colloidal particles are important in defining the mechanical response of soft gels.BACKGROUND Evidence shows that computerized self-help interventions are effective for reducing symptoms of depression. One such intervention, SPARX, is a gamified mobile computerized cognitive behavioral therapy (cCBT) developed for adolescents in New Zealand, which was shown to be as effective as usual care for young people with mild-to-moderate symptoms of depression. However, gamified cCBT has not yet been tested in Japan. OBJECTIVE This trial is designed to investigate whether a Japanese-adapted version of SPARX improves depressive symptoms in Japanese university students with mild-to-moderate depressive symptoms. METHODS In this 7-week, multicenter, stratified, parallel-group, superiority randomized trial, participants will be allocated to either a treatment condition (SPARX) or a wait-list control condition. SPARX is a fully automated program, which will be delivered to the mobile phone or tablet device of the participants. SPARX is designed as an interactive fantasy game to guide the user through sevenal review board approval in September 2019. Data collection began in April 2019. CONCLUSIONS Results of this trial may provide further evidence for the efficacy of gamified cCBT for the treatment of depression and, specifically, provide support for using SPARX with Japanese university students. TRIAL REGISTRATION Japan Primary Registries Network UMIN000034354; https//tinyurl.com/uu7xd77. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) DERR1-10.2196/15164. ©Kengo Yokomitsu, Tomonari Irie, Mayu Sekiguchi, Ayako Shimizu, Hirofumi Matsuoka, Sally N