Tobin Tran (prisongender3)

Taken together, the current study demonstrated sexual dimorphism in VAT-Treg localization in obese mice. PF-05221304 nmr Estrogen may attenuate obesity-associated chronic inflammation partly through altering chemokine-related VAT-Treg localization in females.BACKGROUND There are still limited studies comprehensively examining the diagnostic performance of neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C in contrast-induced nephropathy (CIN). The study aimed to investigate and compare the predictive value of NGAL and cystatin C in the early diagnosis of CIN. METHODS AND MATERIALS We searched the PubMed, EMBASE and Cochrane Library databases until November 10, 2019. The methodological quality of the included studies was assessed by the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool. Bivariate modeling and hierarchical summary receiver operating characteristic (HSROC) modeling were performed to summarize and compare the diagnostic performance of blood/urine NGAL and serum cystatin C in CIN. Subgroup and meta-regression analyses were performed according to the study and patient characteristics. RESULTS Thirty-seven studies from thirty-one original studies were included (blood NGAL, 1840 patients in 9 studies; urine NGAL, 1701 patients in 10 studies; serum cystatin C, 5509 patients in 18 studies). Overall, serum cystatin C performed better than serum/urine NGAL (pooled DOR 43 (95%CI 12-152); AUROC 0.93; λ 3.79); serum and urine NGAL had a similar diagnostic performance (pooled DOR 25 (95%CI 6-108)/22(95%CI 8-64); AUROC 0.90/0.89; λ 3.20/3.08). Meta-regression analysis indicated that the sources of heterogeneity might be CIN definition, assays, and nationalities. CONCLUSION Both NGAL and cystatin C can serve as early diagnostic indicators of CIN, while cystatin C may perform better than NGAL.BACKGROUND Ultra close-range digital photogrammetry (UCR-DP) is emerging as a robust technique for 3D model generation and represents a convenient and low-cost solution for rapid data acquisition in virtual anthropology. OBJECTIVES This systematic review aims to analyse applications, technical implementation, and performance of UCR-DP in skeletal anthropology. METHODS The PRISMA guidelines were applied to the study. The bibliographic search was performed on March 1st, 2019 using Scopus and MEDLINE databases to retrieve peer-reviewed studies accessible in English full-text. The authors worked independently to select the articles meeting inclusion criteria, upon discussion. Studies underwent to quantitative and qualitative syntheses. RESULTS Twenty-six studies were selected. The majority appeared in 2016 or after and were focused on methodological aspects; the applications mainly dealt with the documentation of skeletal findings and the identification or comparison of anatomical features and trauma. Most authors used commercial software packages, and an offline approach. Research is still quite heterogeneous concerning methods, terminology and quality of results, and proper validation is still lacking. CONCLUSIONS UCR-DP has great potential in skeletal anthropology, with many significant advantages versatility in terms of application range and technical implementation, scalability, and photorealistic restitution. Validation of the technique, and the application of the cloud-based approach, with its reduced requirements relating to hardware, labour, time, and cost, could further facilitate the sharing of large collections for research and communication purposes.Acinetobacter baumannii is an opportunistic pathogen of intensive care unit (ICU) patients. A. baumannii colonizes many parts of the body including the gastrointestinal tract. Endemic and epidemic strains are polyclonal. There is no clarity on the origin of polyclonality of A. baumannii. The objective of the study was to define the genetic relatedness of serial isolates and the origin of polyclonality. Serial rectal isolates from ICU patients whose re