Bowers Capps (peacebottle63)

The classical Chinese herbal prescription Beimu-Gualou formula (BMGLF) has been diffusely applied to the treatment of respiratory diseases, including bronchiectasis. Although concerning bronchiectasis the effects and mechanisms of action of the BMGLF constituents have been partially elucidated, it remains to be determined how the formula in its entirety exerts therapeutic effects. In this study, the multitarget mechanisms of BMGLF against bronchiectasis were predicted with network pharmacology analysis. Using prepared data, a drug-target interaction network was established and subsequently the core therapeutic targets of BMGLF were identified. Furthermore, the biological function and pathway enrichment of potential targets were analyzed to evaluate the therapeutic effects and pivotal signaling pathways of BMGLF. Finally, virtual molecular docking was performed to assess the affinities of compounds for the candidate targets. The therapeutic action of BMGLF against bronchiectasis involves 18 core target p results may provide a basis for novel pharmacotherapeutic approaches for bronchiectasis.Cough variant asthma (CVA) is a unique type of asthma characterized by cough as the only or primary clinical presentation. Inhaled glucocorticoid is the main treatment in clinical practice currently, but its efficacy remains relatively unsatisfactory. Traditional Chinese medicine has certain advantages in the treatment of CVA, and at present, the most commonly used traditional Chinese medicine is Suhuang Zhike Capsule (SZC). The aim of this study was to systematically evaluate the efficacy and safety of SZC in the treatment of CVA using a meta-analysis. A comprehensive search of papers published in the PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature database (CBM), Wanfang Database, and VIP Information (VIP) from January 2018 to June 2019 was conducted. Review Manager 5.3 was used to carry out a meta-analysis of 10 studies that fulfilled the inclusion criteria. In a total of 10 randomized controlled trials, 896 CVA patients were included. The results showed the following (1) compared with conventional Western medicine, SZC can effectively increase the efficacy rate of CVA (RR 1.25, 95% CI, 1.16-1.35, P less then 0.00001) and (2) compared with other traditional Chinese medicines, SZC can effectively increase the efficacy rate of CVA (RR 1.44, 95% CI, 1.01-2.05, P=0.05), In conclusion, our study builds on existing clinical evidence showing that SZC is safe and effective in treating CVA. However, larger randomized controlled trials are required for further validation.The Traditional Chinese Medicine (TCM) Consultation Model for Adherence conceptualises the consultation process specific to patient adherence. It can be used to improve patient persistence with treatment by TCM practitioners and possibly other health professionals. The aim of this research was to determine the applicability of the TCM Consultation Model for Adherence in the wider complementary and alternative medicine (CAM) setting. A survey containing validated questionnaires and items developed specifically to test the model was administered online in the United Kingdom. SPSS 25 was used to perform Spearman's correlations and Mann-Whitney U tests on the data. In total, 101 patients completed the survey. The results showed that patients having a therapeutic relationship and trusting in their practitioner was associated with overall adherence to CAM, while patients feeling supported was associated with all types of adherence to CAM. Specific behaviours of the TCM Consultation Model for Adherence that were positively correlated with adherence to CAM were identified. They could potentially be used by CAM practitioners to improve their patients' adherence with treatment.Yin-tonic herbal medicines have been shown to possess properties that make skin healthy by nourishing within various organs of t