Aguirre Wallace (ownerbill98)

4% (3,053) during surgeon low-volume days; 175 patients in the high-volume group and 73 patients in the low-volume group (1.7% each) achieved visual acuity worse than 3/60. There were comparable posterior capsular rupture rates (423, 1.78%) during high- and low- volume months and 21 cases (0.09%) of postoperative endophthalmitis were noted. CONCLUSIONS MSICS can be used to tackle large cataract backlogs in developing countries as good visual outcomes can be achieved in high-volume settings if standard protocols for quality control are followed.PURPOSE To analyze the characteristics and factors associated with intraocular lens (IOL) tilt and decentration after uneventful phacoemulsification with IOL implantation. SETTING Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China. DESIGN Cross-sectional study. METHODS All patients underwent a general ophthalmologic examination and anterior segment photography. IOL tilt and decentration were measured with a second-generation anterior segment optical coherence tomography Casia2. Univariate and multivariate regression analyses were performed to assess the association between IOL tilt and decentration with ocular biometric and systemic parameters, and the visual acuity. RESULTS IOLs showed an average tilt of 4.8 degrees towards the inferotemporal direction and the average decentration was 0.21 mm. Both eyes presented a mirror symmetry relationship. Twenty-two eyes (11.22%) had a tilt greater than 7 degrees, and 21 eyes (10.72%) had a decentration more than 0.4 mm. Multivariate regression analysis showed previous pars plana vitrectomy (PPV) and short axial length (AL) were associated with greater IOL tilt (P = 0.014 and P less then 0.001). In addition, long AL, thicker lens and less capsulorhexis-IOL overlap were positively correlated with decentration (P less then 0.001, P=0.029 and P=0.026). Corrected distance visual acuity did not directly correlate to IOL tilt and decentration (P=0.417 and P= 0.550). CONCLUSIONS PPV history and short AL were associated with greater IOL tilt, while longer AL, thicker lens, and overlarge capsulorhexis contribute to greater decentration. Implantation of toric and multifocal IOLs in these patients should be cautious.PURPOSE To compare loteprednol etabonate (LE) gel 0.5% with prednisolone acetate (PA) suspension 1% for the treatment of inflammation after cataract surgery in children. SETTING Eleven sites in the United States. DESIGN Randomized, double-masked, parallel-group, noninferiority study. METHODS Eligible patients were ≤11 years of age and candidates for routine, uncomplicated cataract surgery. Patients were randomized to a 4-week post-surgical regimen with LE gel 0.5% or PA 1%, twice on the day of surgery, 4 times daily for 2 weeks, twice daily for 1 week, and once daily for 1 week. Assessments included anterior chamber (AC) cells/flare, AC inflammation (ACI), synechiae, precipitates on the implant/cornea, visual acuity, and intraocular pressure (IOP). RESULTS The intent-to-treat population comprised 105 patients (LE gel, n=53; PA 1%, n=52) including 52 patients aged ≤3 years. Patients achieved a similar mean ACI grade on postoperative day 14 (primary efficacy endpoint) whether treated with LE gel 0.5% or PA 1% (difference = 0.006, 2-sided 95% CI = -0.281 to 0.292). Similar ACI outcomes were observed in patients ≤3 years of age. LE gel and PA 1% also appeared equally effective in resolving inflammation at all visits (days 7, 14, 28 post-surgery), based on categorical distributions of ACI, AC cells, and AC flare scores/grades (P≥0.06). Synechiae and corneal/implant precipitates occurred infrequently with no significant differences between groups. No safety or tolerability concerns were identified, including no treatment-related IOP increases. CONCLUSIONS LE gel 0.5% was safe and effective in treating pediatric post-cataract surgical inflammation, with similar outcomes as PA 1%.BACKGROUND Often, only saphenous vein grafts (SVGs) ar