Thorpe Gould (orderwine93)

809) is higher than that of the left colon (AUC = 0.735), and the accuracy of predicting the cleanliness of the right colon intestinal tract by the cleanliness of the left colon intestinal tract is relatively low. Conclusion Intestinal cleanliness gradually deteriorates from the direction of the insert. It is not reliable to predict the right side of poor cleanliness by using the left colon intestinal cleanliness (BBPS 0-1 score). It should continue to further endoscopy. When the cleanliness of the transverse colon is poor, then stopping further endoscopy is considered. Copyright © 2020 Zhou Haibin et al.The recently proposed multiobjective particle swarm optimization algorithm based on competition mechanism algorithm cannot effectively deal with many-objective optimization problems, which is characterized by relatively poor convergence and diversity, and long computing runtime. In this paper, a novel multi/many-objective particle swarm optimization algorithm based on competition mechanism is proposed, which maintains population diversity by the maximum and minimum angle between ordinary and extreme individuals. And the recently proposed θ-dominance is adopted to further enhance the performance of the algorithm. The proposed algorithm is evaluated on the standard benchmark problems DTLZ, WFG, and UF1-9 and compared with the four recently proposed multiobjective particle swarm optimization algorithms and four state-of-the-art many-objective evolutionary optimization algorithms. The experimental results indicate that the proposed algorithm has better convergence and diversity, and its performance is superior to other comparative algorithms on most test instances. Copyright © 2020 Wusi Yang et al.Diabetic retinopathy (DR) is a condition that develops after long-lasting and poorly handled diabetes and is presently the main reason for blindness among elderly and youth. Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that are involved in carbohydrate and fatty-acid metabolism and have also been associated with DR. Three PPAR isoforms are known PPARG, PPARA, and PPARD. In the present study, we retrieved articles reporting associations between PPARs and DR from PubMed database and compiled the data in two catalogues, for human and animal models. Extracted data was then complemented with additional relevant genomic information. Seven retrieved articles reported testing an association between PPARs with DR in human. Four of them concluded association of PPARG and PPARA with DR in European and Asian populations, having a protective role on DR development. One study reported pathogenic role of PPARG, while two articles reported no association between PPARG and DR among Indian and Chinese populations. Six retrieved articles reported testing of involvement of PPARG and PPARA in DR in animal models, including mouse and rat. The review includes case-control studies, meta-analysis, expression studies, animal models, and cell line studies. Despite a large number of documented sequence variants of the PPAR genes available in genome browsers, researchers usually focus on a small set of previously reported variants. Data extraction from Ensembl genome browser revealed several sequence variants with predicted deleterious effect on protein function which present candidates for further experimental validation. Results of the present analysis will enable more holistic approach for understanding of PPARs in DR development. Additionally, developed catalogues present a baseline for standardized reporting of PPAR-phenotype association in upcoming studies. Copyright © 2020 Špela Tajnšek et al.Bone age assessment (BAA) is an essential topic in the clinical practice of evaluating the biological maturity of children. Because the manual method is time-consuming and prone to observer variability, it is attractive to develop computer-aided and automated methods for BAA. In this paper, we present a fully automatic BAA method. To elimin