Hart Nymand (milkoption6)
The successful development of the image denoising techniques for low-dose computed tomography (LDCT) was largely owing to the public-domain availability of spatially-aligned high- and low-dose CT image pairs. Even though low-dose CT scans are also highly desired in dental imaging, public-domain databases of dental CT image pairs have not been established yet. In this paper, we propose a dental CT image denoising method based on the transfer learning of a generative adversarial network (GAN) from the public-domain CT images. We trained a generative adversarial network with the Wasserstein loss function (WGAN) using 5,100 high- and low-dose medical CT image pairs of human chest and abdomen. For the generative network of GAN, we used the U-net structure of five stages to exploit its high computational efficiency. After training the proposed network, named U-WGAN, we fine-tuned the network with 3,006 dental CT image pairs of two different human skull phantoms. For the high- and low-dose scans of the phantoms, we set the tube current of the dental CT to 10 mA and 4 mA, respectively, with the tube voltage set to 90 kVp in both scans. We applied the trained network to denoising of low-dose dental CT images of dental phantoms and adult humans. The U-net processed images showed over-smoothing effects even though U-net had a good performance in the quantitative metrics. U-WGAN showed similar denoising performance to WGAN, but it reduced the computation time of WGAN by a factor of 10. The fine-tuning procedure in the transfer learning scheme enhanced the network performance in terms of the quantitative metrics, and it also improved visual appearance of the processed images. Even though the number of fine-tuning images was very limited in this study, we think the transfer learning scheme can be a good option for developing deep learning networks for dental CT image denoising.A novel model of the skin dose in whole-body UV phototherapy treatment cabins is presented. The model is based on an analysis of the thermal radiation exchange between two surfaces, in this case the UV source and the patient. It is shown to allow analytical treatment of the multiple internal reflections in a treatment cabin that account for around 40% of the skin irradiance. The model provides predictions of the absolute irradiance at the skin and shielding factors in seven different UVA and NB-UVB cabins that are within 6% of those measured using a calibrated radiometer and within 12% for all nine cabins. The model predicts reducing skin irradiances with increasingly patient size, a trend demonstrated in clinical measurements. The exact sensitivity to patient size in automated cabin dosimetry systems, however, varies with in-built sensor positioning. The potential to extend the use of the model to investigate improved design of automated dosimetry systems is discussed.Alzheimer's Disease (AD) begins several years before the symptoms develop. All trans-Retinal supplier It starts with Mild Cognitive Impairment (MCI) which can be separated into Early MCI and Late MCI (EMCI and LMCI). Functional connectivity analysis and classification are done among the different stages of illness with Functional Magnetic Resonance Imaging (fMRI). In this study, in addition to the four stages including healthy, EMCI, LMCI, and AD, the patients have been tracked for a year. Indeed, the classification has been done among 7 groups to analyze the functional connectivity changes in one year in different stages. After generating the functional connectivity graphs for eliminating the weak links, three different sparsification methods were used. In addition to simple thresholding, spectral sparsification based on effective resistance and sparse autoencoder were performed in order to analyze the effect of sparsification routine on classification results. Also, instead of extracting common features, the correlation matrices were reshaped to a correlation vector and used as a feature vector to