Vazquez Guthrie (leadlip28)

Malignant transformation is a rare complication of the mature cystic teratoma of the ovary. Most of these histologic types are squamous cell carcinoma, and other types are exceptionally rare. Here, we present an extremely rare histology of malignant transformation, an undifferentiated carcinoma, arising in mature cystic teratoma of the ovary. A 48-year-old woman was referred due to abdominal distension and palpable pelvic mass. Computed tomography showed 16- and 12-cm-diameter mixed solid and cystic tumors in bilateral ovaries. Surgical exploration revealed bilateral ovarian tumors with multiple nodules on the whole peritoneum, liver capsule, and diaphragm. Cytoreductive surgery was performed, leaving less then 1 cm tumors. On pathologic review, the tumor was confirmed as undifferentiated with an adenosquamous carcinoma component arising in mature cystic teratoma. The patient died 7 days postoperatively due to uncontrolled malignant ascites and pleural effusion. We report a case of undifferentiated carcinoma arising from mature cystic teratoma, and we review the clinicopathologic features of this rare case. Primary cardiac lymphoma (PCL) is a rare cardiac neoplasm. The most common type is diffuse large B-cell lymphoma, which mainly involves the right atrium and right ventricle. Its clinical manifestations are not specific. It is usually found late and the prognosis is poor. PCL is more common in immunodeficient patients. In view of the rarity of PCL, we have made a case report and a brief literature review. We documented an elderly male patient with Burkitt's lymphoma diagnosed by echocardiography and percutaneous biopsy because of chest tightness. Chemotherapy was given to the patient, and the patient's condition was alleviated without recurrence. Primary cardiac lymphoma is a highly malignant tumor. Early detection, diagnosis and treatment are crucial to the prognosis of PCL. At present, the most effective treatment is chemotherapy. There are more chemotherapy schemes and treatment methods worth studying. Primary cardiac lymphoma is a highly malignant tumor. Early detection, diagnosis and treatment are crucial to the prognosis of PCL. At present, the most effective treatment is chemotherapy. There are more chemotherapy schemes and treatment methods worth studying.The hallmark of eosinophilic fasciitis (EF) is painful symmetric skin stiffness and limb sclerosis with deep fascia inflammation. Two cases of unilateral EF have been reported in the literature but were not related to strenuous physical activity. In this report, a young female presenting with unilateral scleroderma-like skin changes, blood and tissue eosinophilia, and hypergammaglobulinemia proven to be EF after strenuous physical activity is described. This case represents the first case reported in the current literature of unilateral EF after vigorous exercise. A skin to muscle biopsy and magnetic resonance imaging (MRI) study indicated classic EF features. Cases of unilateral eosinophilic fasciitis are under-recognized and have rarely been described in the literature. EF requires a high index of suspicion to be diagnosed accurately and differentiated from another scleroderma variant, especially localized types. Early diagnosis and management of unilateral EF are very crucial because EF management and prognosis are completely different from other scleroderma mimics. EF heals rapidly in response to glucocorticoid or combination therapy. In the current case, corticosteroids alone failed to induce complete disease remission, but with the addition of methotrexate, complete resolution of both skin and systemic features was obtained. She is now in good health with no medication use. The current literature review indicates that this the first reported case of unilateral EF after vigorous exercise.Interleukin-32 (IL-32) as a pro-inflammatory cytokine participates in the progression of inflammation and cancer. Ovarian cancer (OC) accou