Snider Weaver (koreanjeff07)
Furthermore, the importance of promoting healthcare professionals' wellbeing has been advocated. Family caregivers, as well as patients' organizations - should be trained and engaged to increase the effectiveness of interventions dedicated to patients. Finally, experts agreed that digital technologies should be considered as a crucial enhancer for patient engagement in chronic care.Augmented Reality (AR) and Mixed Reality (MR) devices have evolved significantly in the last years, providing immersive AR/MR experiences that allow users to interact with virtual elements placed on the real-world. However, to make AR/MR devices reach their full potential, it is necessary to go further and let them collaborate with the physical elements around them, including the objects that belong to the Internet of Things (IoT). Unfortunately, AR/MR and IoT devices usually make use of heterogeneous technologies that complicate their intercommunication. Moreover, the implementation of the intercommunication mechanisms requires involving specialized developers with have experience on the necessary technologies. To tackle such problems, this article proposes the use of a framework that makes it easy to integrate AR/MR and IoT devices, allowing them to communicate dynamically and in real time. The presented AR/MR-IoT framework makes use of standard and open-source protocols and tools like MQTT, HTTPS or Node-RED. After detailing the inner workings of the framework, it is illustrated its potential through a practical use case a smart power socket that can be monitored and controlled through Microsoft HoloLens AR/MR glasses. The performance of such a practical use case is evaluated and it is demonstrated that the proposed framework, under normal operation conditions, enables to respond in less than 100 ms to interaction and data update requests.Neurodegenerative diseases (NDs) bear a lot of weight in public health. By studying the properties of the blood-brain barrier (BBB) and its fundamental interactions with the central nervous system (CNS), it is possible to improve the understanding of the pathological mechanisms behind these disorders and create new and better strategies to improve bioavailability and therapeutic efficiency, such as nanocarriers. Microfluidics is an intersectional field with many applications. Microfluidic systems can be an invaluable tool to accurately simulate the BBB microenvironment, as well as develop, in a reproducible manner, drug delivery systems with well-defined physicochemical characteristics. This review provides an overview of the most recent advances on microfluidic devices for CNS-targeted studies. Firstly, the importance of the BBB will be addressed, and different experimental BBB models will be briefly discussed. Subsequently, microfluidic-integrated BBB models (BBB/brain-on-a-chip) are introduced and the state of the art reviewed, with special emphasis on their use to study NDs. Additionally, the microfluidic preparation of nanocarriers and other compounds for CNS delivery has been covered. Scutellarin molecular weight The last section focuses on current challenges and future perspectives of microfluidic experimentation.Parents who lost their only child in the 12 May 2018 Wenchuan earthquake came to be known as the "shidu" (loss of an only child) parents. After the earthquake, they were beneficiaries of free reproductive health services, and most had another child. This study focuses on the psychosocial well-being of those children born to the shidu parents, and explores factors associated with mothers' quality of life (QoL) and their involvement with their children. A cross-sectional survey was conducted in two primary schools in Wenchuan County. A sample of 192 families was analyzed (147 non-shidu and 45 shidu). The statistical analyses indicated that the children of shidu families had poorer peer relationships than children of non-shidu families. Moreover, shidu mothers' expectations of their children's a
