Andrews Vang (hailfrance3)
ter, Tehran University of Medical Sciences.Objective This study aimed to model risky driving and predict its occurrence according to the constructs of personality organization and mentalization considering the role of aggressive driving as a mediator construct. Method A total of 428 individuals (219 men and 209 women) were selected using convenience sampling. The participants completed self-report questionnaires on aggressive driving, risky driving, mentalization and personality organization Also, data were analyzed using structural equating model and weighted regression. Results The results of this study showed a goof fit of the proposed structural model for predicting risky driving after some modifications (CFI = 0.95, RMSEA = 0.09). According to the results of regression weights, personality organization (regression weighted 0.044) and aggressive driving (regression weighted 0.98) were the strongest and mentalization (regression weighted 0.004) was the weakest predictor of risky driving. Aggressive driving was the strongest direct predictor and personality organization the strongest indirect predictor of risky driving. Conclusion Risky driving is a function of direct and indirect personal factors. Moreover, emotional factors have a direct effect on risky driving and more substantial constructs, such as personality, have an indirect effect on risky driving. Copyright © Psychiatry & Psychology Research Center, Tehran University of Medical Sciences.Objective Schizophrenia is a complicated mental disorder that affects about 1% of the world's population. It is a complex disease and is approximately 80% inherited. One of the candidate genes in schizophrenia is transcription factor 4 (TCF4), which is positioned on chromosome 18 and is a transcription factor that plays a role in the transcription of Neurexin 1(NRXN1) gene, which is one of the candidate genes for developing schizophrenia. This case-control study aimed to investigate the correlation of TCF4 rs13381800 and NRXN1 rs17039988 polymorphisms with the risk of schizophrenia in a sample of Iranian patients with schizophrenia. Method A total of 200 individuals were included in this study 100 patients with schizophrenia (65 males and 35 females), with the mean age of 40.80 ± 11.298 years, and 100 as a control group (63 males and 37 females), with the mean age 32.92 ± 7.391 years. Allele specific polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) were done, respectively, for genotyping of rs13381800 (T/C) and rs17039988 (A/C) polymorphisms. Results The results showed that the frequency of C / C genotype in rs13381800 in patients' group was 9%, while it was 13% in the control group. Also, the frequency of C / C genotype in rs17039988 was 9% in patients and 7% in control groups. Statistical analysis of polymorphisms showed no correlation between patients and controls in rs13381800 (OR = 1.51; CI = 95%; P = 0.366) and rs17039988 (OR = 0.76; CI = 95%; P = 0.602). Conclusion No significant difference was found between rs13381800 and rs17039988 genotypes between patients and control groups in terms of gender, age and education in the patients group. Our study suggests that there was no correlation between desired polymorphisms with schizophrenia in the studied population. Copyright © Psychiatry & Psychology Research Center, Tehran University of Medical Sciences.Objective Body mass index undergoes a substantial change in some psychiatric disorders. This study aimed to explore the status of body mass index (BMI) in different psychiatric disorders in a national survey among children and adolescents and to identify the role of gender in this regard. Method A total of 30 532 children and adolescents were randomly selected using cluster sampling method with equal blocks of three age groups and two genders. Psychiatric disorders were assessed using a standardized face-to-face diagnostic interview of Kiddie Schedule for Affective Disorders and Schizoph