McClanahan Foley (flighthouse69)

Our results demonstrate that concerted structural changes on the microsecond time scale serve as the regulatory switch in FixL.With the rapid development of the nuclear industry, how to deal with radioactive iodine waste in a timely and effective manner has become an important issue to be solved urgently. Herein, the defect-engineering strategy has been applied to develop a metal-organic framework (MOF)-based solid adsorbent by using the classical UiO-type Hf-UiO-66 as an example. After simple acid treatment, the produced defect-containing Hf-UiO-66 (DHUN) not only retains its topological structure, high crystallization, and regular shape but also shows a great increase in the Brunauer-Emmett-Teller value and pore size in comparison with the original Hf-UiO (HUN). These formed defects within DHUN have been demonstrated to be important for the great enhancement of the iodine capture and following application in computed tomography imaging in vitro. This present work gives a new insight into the control and formation of defect sites, and this simple and efficient defect-engineering strategy also shows great promise for the development of novel solid adsorbents and other functional MOF materials.Adsorption of uranium onto goethite is an important partitioning process that controls uranium mobility in subsurface environments, for which many different surface complexation models (SCMs) have been developed. While individual models can fit the data for which they are parameterized, many perform poorly when compared with experimental data covering a broader range of conditions. There is an imperative need to quantitatively evaluate the variations in the models and to develop a more robust model that can be used with more confidence across the wide range of conditions. We conducted an intercomparison and refinement of the SCMs based on a metadata analysis. By seeking the globally best fit to a composite dataset with wide ranges of pH, solid/sorbate ratios, and carbonate concentrations, we developed a series of models with different levels of complexity following a systematic roadmap. The goethite-uranyl-carbonate ternary surface complexes were required in every model. For the spectroscopically informed models, a triple-plane model was found to provide the best fit, but the performance of the double-layer model with bidentate goethite-uranyl and goethite-uranyl-carbonate complexes was also comparable. Nevertheless, the models that ignore the bidentate feature of uranyl surface complexation consistently performed poorly. The goodness of fitting for the models that ignore adsorption of carbonate and the charge distributions was not significantly compromised compared with that of their counterparts that considered those. This approach of model development for a large and varied dataset improved our understanding of U(VI)-goethite surface reactions and can lead to a path for generating a single set of reactions and equilibrium constants for including U(VI) adsorption onto goethite in reactive transport models.The design of well-defined monodispersed self-assembling semi-synthetic proteins is emerging as a promising research avenue. These proteins hold great potential to be used as scaffolds for various protein nanotechnology applications. Currently, there are very few chemical methods reported; however, they suffer from elaborate multistep organic synthesis. Herein, we report a new chemical methodology for the rapid synthesis of a diverse set of semi-synthetic protein families, which include protein amphiphiles, facially amphiphilic protein-dendron conjugates, and pH-sensitive protein-dendron conjugates. This chemical method holds great potential to access a wide variety of semi-synthetic proteins in a short time.The ultraviolet (UV) photodissociation dynamics of the jet-cooled cyclohexyl (c-C6H11) radical is studied using the high-n Rydberg atom time-of-flight (HRTOF) technique. The cyclohexyl radical is produced by the 193 nm photodisso