Reed Santana (eyebun39)

7% were taking anxiolytics, with greater drug consumption in the insomnia group. In a multivariate analysis, GPs who personally consumed these medications prescribed significantly more of them to patients, whereas their insomnia status had less impact. Other factors such as gender and type of practice were not associated with a higher prescription rate. Our results indicate that GPs' personal drug consumption can have a significant impact on the management of their patients, therefore suggesting that actions towards GPs' health improvement may also benefit their patients and the public. © 2020 European Sleep Research Society.Different types of glycosides extract of fenugreek have shown androgenic and anabolic effect in male. The aim of the study was to evaluate the effect of fenugreek extract on total testosterone levels in male. Medline via PubMed, Scopus databases, Cochrane Library, Web of Science, and Google Scholar were searched up to November 2018 for randomized clinical trials comparing intake of fenugreek extract with control group. Data on change in serum total testosterone were pooled using random-effects models. A total of four trials were included. Fenugreek extract has a significant effect on total serum testosterone. Results from clinical trials suggest that fenugreek extract supplement has an effect on serum total testosterone levels in male. © 2020 John Wiley & Sons, Ltd.BACKGROUND The development of a terminology system is essential to allow uniformity in reporting serous fluid specimens. An important topic to cover is the issue of specimen adequacy. In the present study, we aimed to evaluate whether there is a correlation between number of mesothelial cells and overall test's improved sensitivity and adequacy control. METHODS Cases of negative pleural fluids with concomitant positive pleural biopsies were selected from two referral institutions, with observation of the number of mesothelial cells in 10 high power fields, comparing the results with a control group (cases with negative biopsies, i.e. true negatives). Comparisons were conducted using the nonparametric Mann-Whitney U test. Data were analyzed for sensitivity and specificity derived from the Receiver Operating Characteristics (ROC) curve. For the choice of an optimal cutoff of mesothelial cells, receiver-operating curve analysis was constructed and the Youden index was calculated. RESULTS A total of 112 pleural effusions with paired pleural biopsies were studied. There was no difference in distributions of the number of mesothelial cells between cases with a positive biopsy (false negatives) and the control group (median=39 vs. median=30, respectively, p-value=0.974). However, simple logistic regression found a cutoff of 750 cells per 10 HPF as an optimal number for improved sensitivity (72.7%), with fair discriminatory power. CONCLUSIONS Enumeration of mesothelial cells may improve the sensitivity of the cytologic diagnosis of MPE, serving as an internal quality control for the test's overall accuracy. This article is protected by copyright. All rights reserved.In the absence of vision, spatial representation may be altered. When asked to compare the relative distances between three sounds (i.e., auditory spatial bisection task), blind individuals demonstrate significant deficits and do not show an event-related potential response mimicking the visual C1 reported in sighted people. However, we have recently demonstrated that the spatial deficit disappears if coherent time and space cues are presented to blind people, suggesting that they may use time information to infer spatial maps. In this study, we examined whether the modification of temporal cues during space evaluation altered the recruitment of the visual and auditory cortices in blind individuals. We demonstrated that the early (50-90 ms) occipital response, mimicking the visual C1, is not elicited by the physical position of the sound, but by its virtual position suggested by its te