Short Dupont (doorcrab9)
There was no difference in short-term survival between VA-ECMO treated patients and control patients (RR 0.91, 95% CI 0.71-1.16). In acute PE patients undergoing VA-ECMO, age > 60 years was associated with lower survival (RR 0.72, 95% CI 0.52-0.99), surgical embolectomy was associated with higher survival (RR 1.96, 95% CI 1.39-2.76) and pre-ECMO cardiac arrest showed a trend toward lower survival (RR 0.88, 95% CI 0.77-1.01). The other evaluated factors were not associated with a difference in survival. At present, there is insufficient evidence that VA-ECMO treatment improves short-term survival of acute PE patients. Low quality evidence suggest that VA-ECMO patients aged ≤60 years or who received SE have higher survival rates. Considering the limited evidence derived from the present data, this study emphasizes the need for prospective studies. PROSPERO CRD42019120370. PROSPERO CRD42019120370. Margin status and lymph node metastasis are the most important prognostic factors for oral cancers. However, while adequate surgical resection is crucial for local control and prognosis, the definition of clear margins has long been a subject of debate. In this study, we analyzed data from a nationwide population-based cancer registry database and evaluated the impact of surgical margins on cancer-specific survival (CSS) and overall survival (OS) as well as the optimal cutoff of adequate surgical margins. This analysis included all cases of oral cancer diagnosed from 2011 to 2017 that were reported to the Taiwan Cancer Registry database. The staging system was converted from American Joint Committee on Cancer (AJCC) version 7 to AJCC version 8. Kaplan-Meier analysis and Cox proportional-hazards regression were performed to identify covariates that were significantly associated with CSS and OS. Between 2011 and 2017, 15,654 of a total of 36,091 cases diagnosed with oral cancers were included in the final analyses. Advanced N stage, positive margins, and advanced T stage are the leading risk factors for poor CSS and OS. When surgical margins were subdivided into 1-mm intervals from 5mm to positive margin, we found that surgical margins <4mm and <5mm predict poor CSS and OS, respectively. This is the first nationwide, population-based cohort to revisit the question of the adequate surgical margins for oral cancers. SAR131675 We conclude that surgical margins ≥4mm and ≥5mm are adequate for good CSS and OS, respectively. This is the first nationwide, population-based cohort to revisit the question of the adequate surgical margins for oral cancers. We conclude that surgical margins ≥4 mm and ≥5 mm are adequate for good CSS and OS, respectively.Whether human categorization of visual stimuli as faces is optimal for full-front views, best revealing diagnostic features but lacking depth cues, remains largely unknown. To address this question, we presented 16 human observers with unsegmented natural images of different living and non-living objects at a fast rate (f = 12 Hz), with natural face images appearing at f/9 = 1.33 Hz. Faces posing all full-front or at ¾ side view angles appeared in separate sequences. Robust frequency-tagged 1.33 Hz (and harmonic) occipito-temporal electroencephalographic (EEG) responses reflecting face-selective neural activity did not differ in overall amplitude between full-front and ¾ side views. Despite this, alternating between full-front and ¾ side views within a sequence led to significant responses at specific harmonics of .67 Hz (f/18), objectively isolating view-dependent face-selective responses over occipito-temporal regions. Critically, a time-domain analysis showed that these view-dependent face-selective responses reflected only an earlier response to full-front than ¾ side views by 8-13 ms. Overall, these findings indicate that the face-selective neural representation is as robust for ¾ side faces as for full-front f