Poulsen Nguyen (dishenemy8)

The translocation of chemical insecticides in corn plants could enhance the control of Spodoptera frugiperda, based on their application form. Chlorantraniliprole and cyantraniliprole were applied via seed treatment and foliar spray in corn (VE and V3) to characterize the systemic action of both molecules in leaves that appeared after application. Bioassays with S. frugiperda and chemical quantification in LC-MS/MS confirmed the absorption and upward translocation of chlorantraniliprole and cyantraniliprole by xylem to new leaves. Both insecticides caused the mortality of larvae up to stage V6 (57.5±9.5% for chlorantraniliprole and 40±8.1% for cyantraniliprole), indicating the translocation of insecticides into leaves of corn plants when applied via seed treatment. However, the translocation of chlorantraniliprole and cyantraniliprole from sprayed leaves to new leaves was not observed, regardless of the stage of application plus the next first, second and third stages. An increased dosage of cyantraniliprole did not influence on its translocation in plant tissues, however, it influenced on the present amount of active ingredient. The application of chlorantraniliprole and cyantraniliprole in seed treatment is an important alternative for integrated pest management. The absorption and redistribution capacity of chlorantraniliprole and cyantraniliprole throughout the plant confer a prolonged residual action with satisfactory control of S. frugiperda.A fair path to achieve a sustainable world would imply reducing the eventual negative effects linked to the production process while increasing economic output, which is referred to in the literature as impact decoupling. This article aims to assess whether global consumption chains are currently on the decoupling path or not, from a social point of view. Specifically, we address the working conditions which developed societies' lifestyle sparked at a distance in global factory countries, focusing on the most harmful consequences of an indecent work. Additionally, we determine the kind of decoupling observed through the new concept of social footprints' elasticities with respect to final demand for each region. We employ a Multi-Regional Input-Output model and an own elaboration database of social impacts concerning undignified working conditions. Results indicate that most countries achieved the goal of decoupling occupational injuries -both fatal and non-fatal- from production, while results for forced labour show a slower and sometimes uncertain process of decoupling. European Union and United States' footprints have been reduced overtime for the three impacts. However, more than half of these footprints are still generated by imports, mainly from developing regions.Snakebite is a neglected tropical disease that results in a variety of systemic and local pathologies in envenomed victims and is responsible for around 138,000 deaths every year. Many snake venoms cause severe coagulopathy that makes victims vulnerable to suffering life-threating haemorrhage. The mechanisms of action of coagulopathic snake venom toxins are diverse and can result in both anticoagulant and procoagulant effects. However, because snake venoms consist of a mixture of numerous protein and peptide components, high throughput characterizations of specific target bioactives is challenging. In this study, we applied a combination of analytical and pharmacological methods to identify snake venom toxins from a wide diversity of snake species that perturb coagulation. To do so, we used a high-throughput screening approach consisting of a miniaturised plasma coagulation assay in combination with a venom nanofractionation approach. Twenty snake venoms were first separated using reversed-phase liquid chromaing the rapid identification and fractionation of coagulopathic toxins, thereby enabling specific targeting of these toxins by new therapeutics such as monoclonal antibodies and small molecule inhibitors.Cholera