Lindgreen Brogaard (burnwine48)

Whereas a growing bulk of work has demonstrated that both adults and children are sensitive to frequently occurring word sequences, little is known about the potential role of meaning in the processing of such multiword chunks. Here, we take a first step toward assessing the contribution of meaningfulness in the processing of multiword sequences, using items that varied in chunk meaningfulness. In a phrasal-decision study, we compared reaction times for triads of three-word sequences, corresponding to idiomatic expressions, compositional phrases, and phrasal fragments, while controlling for phrase and substring frequencies. Chunk meaningfulness, as assessed by a separate subjective rating study, was found to speed up decision times for all three types of strings The more meaningful a multiword sequence was judged to be, the faster it was processed, independently of whether it was idiomatic, compositional in nature, or a phrasal fragment. These results highlight the importance of taking meaning into account when considering the processing of multiword chunks, consistent with predictions of construction-based approaches to language. The aim was to evaluate, in patients with atrial fibrillation (AF) and acute ischemic stroke, the association of prior anticoagulation with vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) with stroke severity, utilization of intravenous thrombolysis (IVT), safety of IVT, and 3-month outcomes. This was a cohort study of consecutive patients (2014-2019) on anticoagulation versus those without (controls) with regard to stroke severity, rates of IVT/mechanical thrombectomy, symptomatic intracranial hemorrhage (sICH), and favorable outcome (modified Rankin Scale score 0-2) at 3 months. Of 8,179 patients (mean [SD] age, 79.8 [9.6] years; 49% women), 1,486 (18%) were on VKA treatment, 1,634 (20%) on DOAC treatment at stroke onset, and 5,059 controls. Stroke severity was lower in patients on DOACs (median National Institutes of Health Stroke Scale 4, [interquartile range 2-11]) compared with VKA (6, [2-14]) and controls (7, [3-15], p < 0.001; quantile regression β -2.1, 95% confidence inte AF was associated with decreased admission stroke severity at onset and a remarkably low rate of IVT. Overall, patients on DOAC might have better functional outcome at 3 months. Further research is needed to overcome potential restrictions for IVT in patients taking DOACs. learn more ANN NEUROL 2021;8942-53. To investigate which type of exercise is the most effective for people with mild cognitive impairment (MCI) or dementia. Exercise is recommended as a promising intervention for people with cognitive impairment. However, which type of exercise is the most beneficial for people with MCI or dementia seems still unclear. The objective of this article is to assess the relative effectiveness of different types of exercise on cognitive function in people with MCI or dementia using network meta-analysis. Systematic review, meta-analysis, and network meta-analysis. We will systematically search electronic databases including PubMed, Cochrane Central Register of Controlled Trials, EMBASE, Web of Science, SPORTDiscus, and PsycINFO. To avoid missing the eligible literature, we will examine the reference lists of systematic reviews publication since 2017. WHO International Clinical Trials Registry Platform and ClinicalTrials.gov will also be retrieved to identify eligible trials. Two independent researchers will irapy in people with MCI or dementia. PROSPERO registration number CRD42020160620. To develop and validate an acquisition and processing technique that enables fully self-gated 4D flow imaging with whole-heart coverage in a fixed 5-minute scan. The data are acquired continuously using Cartesian sampling and sorted into respiratory and cardiac bins using the self-gating signal. The reconstruction is performed u