Molloy Walther (brassshell5)

This proof-of-concept study presents a computer-based social communication training for spoken workplace interactions called Work-Related Communication (WoRC) training. This program implements didactic training, role-play, and immediate feedback using a simulation approach to improve spoken language performance. The unique target of this training is a category of linguistic markers called politeness markers which are essential for cooperative workplace exchanges. We recruited eight adults with chronic traumatic brain injury. All participants demonstrated reduced politeness marker use in language sampling before treatment. This study had a quasi-experimental treatment design. We measured the rate of politeness marker use (politeness markers per minute) using the Voicemail Elicitation Task and novel role-play tasks, and the La Trobe Communication Questionnaire as outcome (dependent) variables. After training, participants demonstrated an increase in trained and untrained politeness marker use that was significant for the novel role-play tasks. The La Trobe Communication Questionnaire found that familiar conversation partners reported a significant increase in social communication skills. The WoRC program has implications for introducing a sociolinguistic foundation for social communication training in general and specifically for vocational placement. The WoRC program has implications for introducing a sociolinguistic foundation for social communication training in general and specifically for vocational placement. Puerarin is an isoflavone derivative isolated from the traditional Chinese medicine Pueraria Lobelia, which has proven to relieve depression-like behavior. However, its underlying antidepressant mechanisms have been poorly characterized. Herein, we explored whether Puerarin's antidepressant effect is associated with changes in the gut microbiota (GM). The model of depression in mice featuring chronic unpredictable mild stress (CUMS) was eastablished, and its antidepressant effect was estimated by sugar water preference and forced swimming test. Genomic DNA extracted from fecal samples was employed to sequence the 16S rRNA gene for gut microbiota identification. Puerarin (100mg/kg) treatment was found to alleviate the CUMS-induced depression-like behaviors. Furthermore, chronic stress led to pathological microbial flora, which was principally marked by the increased abundance of pathogenic bacteria (Proteobacteria, Flexispira, Desulfovibrio) and the decreased abundance of beneficial bacteria (Firmicutes, Bacillales, Lactobacillus). Intriguingly, puerarin treatment reversed these changes. The specific role and anti-depression mechanism of characteristic gut microflora were not confirmed. Puerarin can remedy stress-induced disruptions of normal gut microflora. It is suggested that the antidepressant mechanism of puerarin may closely interact with restoring beneficial microflora. Puerarin can remedy stress-induced disruptions of normal gut microflora. It is suggested that the antidepressant mechanism of puerarin may closely interact with restoring beneficial microflora. Insufficient sleep duration among university students was commonly associated with many detrimental effects. University students experience substantial environmental and psychological changes. Female and male university students may differ in many spheres. However, most research on sleep duration of university students is based on an aggregate sample rather than digging the sex-specific profiles. The objective of this study is to examine potential sex differences in the correlates of sleep duration and explore the underlying mechanism of correlations. This is a large-scale university-based mental health survey, which was conducted in university students in Qinghai Province in Northwest China in December 2019. A multi-stage logistic regres