Brask Mortensen (bowfly77)

To preserve biodiversity and ecosystem services, company engagement is crucial. However, available data on manager views and perceptions regarding nature conservation in particular is rare. The presented survey data gives insights into current levels and forms of business commitments for nature conservation. The data contributes to understanding business attitudes towards voluntary conservation action and includes information about factors that influence their engagement. Moreover, the data informs about manager perceptions towards the concept of nature conservation credits and, as such, allows for an evaluation of a certified biodiversity and ecosystem services market. Importantly, the dataset contains essential company characteristics to put responses into greater context. click here The scope of the survey is limited to German companies from secondary and tertiary sectors. Companies were sampled through proportional stratified random sampling based on size and location. The data was collected through a self-administered online-survey, conducted in 2019. The database comprises responses of 747 companies that logged into the online system. The survey data were in part analysed through structural equation modelling for an investigation of factors that drive voluntary conservation commitments [1]. Related to this analysis, a subset of 618 companies is available that provided sufficiently completed questionnaires. Both datasets, i.e. the raw data as well as the first subset used for analysis, are hosted in the public repository Open Research Data of the Leibniz Centre for Agricultural Landscape Research (ZALF), Germany. The repository also stores all coding information as well as the questionnaire https//. The dataset can be used, for example, by researchers from the field of environmental business management and strategy.Extracellular vesicles from highly metastatic tumor cells have been shown to mediate epithelial-mesenchymal transition (EMT)-related events in recipient cells. In endometrial epithelial cells, EMT processes are known to be involved in the development of adenomyosis. We aimed to investigate whether adenomyosis-derived extracellular vesicles (AMEVs) are able to induce an EMT process in endometrial epithelial cells. In this study, AMEVs were isolated from patients with adenomyosis and characterized by transmission electron microscopy, Western blot, and nanoparticle tracking. Primary endometrial epithelial cells (EECs) were derived from normal endometrium tissues from patients with leiomyoma and co-cultured with AMEVs in vitro. AMEV uptake was examined by fluorescence confocal microscopy. The invasion of EECs was confirmed by Transwell assay. Immunohistochemistry, Western blot, and qRT-PCR were performed on EECs to illustrate the expression levels of cytokeratin 19, E-cadherin, vimentin, and zinc finger E-box-binding homeobox 1 (ZEB1). The results indicated that the cellular fluorescence intensity gradually increased after 48 h of co-culture, but decreased after 72 h. After co-culturing with AMEVs for 72 h, EECs expressed significantly lower levels of cytokeratin 19 and E-cadherin, and significantly higher levels of vimentin and ZEB1. Together these results demonstrated that AMEVs induce an EMT process and enhance the invasion of EECs. These changes may contribute to the pathogenesis and progression of adenomyosis.Prostate cancer is (PCa) the second leading cause of cancer death in males in the United State, with 174,650 new cases and 31,620 deaths estimated in 2019. It has been documented that epigenetic deregulation such as histone modification and DNA methylation contributes to PCa initiation and progression. EZH2 (enhancer of zeste homolog 2), the catalytic subunit of the Polycomb Repressive Complex (PRC2) responsible for H3K27me3 and gene repression, has been identified as a promising target in PCa. In addition, overexpression of other epigenetic regulators such as DNA methyl