Buus Overgaard (spotgrey1)

**Tesa, Ipamorelin, CJC-1295 no DAC (6/3/3 mg Blend)** The 6 mg Tesa, 3 mg Ipamorelin and 3 mg CJC-1295 blend is a popular combination among athletes and bodybuilders seeking enhanced growth hormone release. By pairing the highly selective GH secretagogue Ipamorelin with the long-acting peptide CJC-1295 (lacking a DAC), the mixture delivers both an acute spike in growth hormone levels and sustained secretion over several days. The 6/3/3 ratio is chosen to balance potency, duration, and cost while minimizing potential side effects. --- ### Tesa Properties Tesa is a proprietary formulation of the synthetic peptide S-P5, designed to stimulate the release of growth hormone (GH) through interaction with GHS-R1a receptors. Key attributes include: - **Potency**: Tesa elicits a robust GH surge within minutes of injection, making it effective for rapid anabolic responses. - **Short Half-Life**: Its plasma half-life is less than an hour, which limits prolonged systemic exposure and reduces the risk of receptor desensitization. - **Rapid Clearance**: Because of its quick elimination, Tesa can be administered multiple times per day if needed without significant accumulation. - **Safety Profile**: Studies indicate low incidence of adverse effects when used at recommended dosages; common concerns are mild injection site reactions and transient headaches. --- ### Ipamorelin Properties Ipamorelin is a hexapeptide GH secretagogue that selectively targets the growth hormone secretagogue receptor (GHS-R1a). Its notable characteristics are: - **High Selectivity**: Unlike older peptides, Ipamorelin has minimal activity on prolactin or cortisol pathways, which reduces unwanted hormonal side effects. - **Short Duration**: The peptide’s effect lasts roughly 30–60 minutes post-injection, allowing precise timing of GH release relative to training sessions. - **Low Appetite Stimulation**: It does not significantly influence hunger hormones, helping users maintain dietary control. - **Stability**: Ipamorelin is stable in solution for several weeks when stored properly, facilitating convenient use. --- ### CJC-1295 Properties CJC-1295 without a DAC (Drug Affinity Complex) is a modified form of the original peptide that enhances GH secretion with an extended action: - **Long Half-Life**: Even without a DAC, CJC-1295 exhibits a half-life of approximately 12–24 hours due to its resistance to proteolytic degradation. - **Sustained GH Release**: Daily injections maintain elevated basal GH levels, supporting tissue repair and lean mass accrual over time. - **Reduced Injection Frequency**: One or two weekly doses can suffice for many users, reducing injection burden. - **Minimal Side Effects**: Clinical data suggest negligible impact on insulin-like growth factor-1 (IGF-1) spikes that could lead to adverse effects. --- ### Other Peptides In addition to the primary blend components, several other peptides are often incorporated into performance protocols: - **GHRP-6 and GHRP-2**: These ghrelin mimetics provide powerful GH surges but carry higher appetite stimulation risks. - **Melanotan II**: Used for skin tanning and libido enhancement; its inclusion is controversial due to safety concerns. - **PEG-IGF-1 (Mecasermin)**: Directly increases IGF-1 levels, promoting anabolic effects but requiring careful monitoring of potential hypoglycemia. - **BPC- cjc-1295 ipamorelin side effects and TB-500**: Tendon and ligament healing peptides that synergize with GH for recovery. Each peptide’s integration depends on individual goals, tolerance, and regulatory considerations.